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JVABIHS AND HYDROPHOBIA.

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JVABIHS AND HYDROPHOBIA. The nlxt olass of facts is a very large one, and of vary great importance, as it tends to point to the possibility that the virus may be at certain stages localised, and therefore locally treated with success. That the poison is so for the first tew minutes we know, since it can be locally destroyed by cautery, acids, or other treatment. It is further remarkable tha when, after the wound has healed, hydrophobia appears the first uneasy sensations are very often in th.. w, .aod or cicatrix itself. Further still, Dr Stokes, of Dublin, reported to Dr. Brown-Sequard. that when he applied a. tourniquet to the bitten limb of a hydro- phobic patient the symptoms at once improved, and even seemed to cease. gfreh may be called symptoms of prluxury local effects but there is a remarkable and large class of evidence to show that possibly the virtu may become locally manifest, after these have ceased, in a secon- dary form. In 1819 (we quote Fleming) Dr. Salvatori, of St. Petersburg, found that the peasants of Galicia were unanimous in stating that underneath the tongues (about the jraenuni) of persons or animals bitten by mad dogs were to be found pustules, which opened about the fourteenth day after the wound. In 1813 a peasant of the Ukraine had called Dr. Maro- chetti's attention to the same fact, and assured him that if these pustules were not opened, and the matter removed within twenty-four hours, the virtu wo aid be re-absorbed, and hydrophobia set in; but if the pusdes were open, discharged, and cauterised, exemption was sure. Maro- chetti affirms that five years later, in Podolia, he verified all this; Xanthos affirms the same thing; and Magiatel, in 1824, after a special investigation, re- ports to the same effect, Turenne and Trousseau both consider these statements worfchy of most serioiis attention, and so does evidently Mr. Fleming, though many other observers have ridiculed, discarded, and even denied them. But it is to be observed, m refer- eace to these failures and denials, that Magistel clearly affirms he never succeeded in finding these pustules, except within very narrow limits, never .in any known case exceeding thirty-four days after the bite; and, we may justly ask, in how many cases does hydrophobia set in so early, and in how many have such appearances been looked for before the well-known symptoms show that the period for such pustules is long since past ? They only last for some twenty-six hours, and it is obvious that only a careful daily search at early periods, apart from other symptoms, could discover them. Another class of facts tend to show the very probable occurrence of the alleged pustules. There are-lint, the remarkable traditions Respecting the worm wider a dog's tongue, extraction of which is sup- posed to prevent his ever going mad. This is clearly expressed so far baek as in Pliny; again in old Anglo- Saxon books; and Dr. Xanthos says the belief has been universal in Greece from time immemorial. Turenne says it is prevalent in Turkey and Roumania; and others have found the same tradition in Poland, in Spain, and the Brazils. We now know it to be a mistake; but tehenee comes itl Mr. Fleming has notieed the extraordinary fact that such a tradition should so prevail from early times in localities so widely separated but has apparently failed to notice its extremely probable connection with some former successful treatment of hydrophobia by removing the pustules referred to. The probability of woo" con- nection is very obvious. Again, such pustules Ifeve o ten been observed in the rabid dog before the later symptoms; and in this animal the period of incuba- tion is shorter and more definite. Here too it is obvious many eases would never be observed; but it is remarkable that in nearly all cases of extensive outbreaks—when, therefore, careful examination would be made—such appearances were found.—Live Stock Journal. g

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