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FOR STOPPING DECAYED TEETH. PRICE 2s. Gd. PATRONIZED BY HER MAJESTY THE QUEEN, His Royal Highness Prince Albert, Her Royal Highness the Duchess of Kent, His Majesty the King of the Belgians, His Majesty the King of Prussia, His Grace the Archbishop of Canterbury, And nearly all the Nobility, the Bishops and the Clergy. MR. THOMAS'S SUCCEDANEUM, FOR filling Decayed Teeth, however large the cavity. It is superior to anything ever before used, as it is Placed in the- tooth in a soft state, without any pressure Or pain, and in a short time becomes as hard as the enamel, and will remain firm in the tooth many years, tendering extraction unnecessary, It arrests all further Progress of decay and renders them again useful in mas- tication All persons can use Mr. THOMAS's SUC- CEDANEUM THEMSELVES WITH EASE, as full directions are enclosed. Prepared only by Messrs. HOWARD & THOMAS, Surgeon IVntists, 64, Berners-street, Oxford-street. London. Price 6.1. Sard by their appointment by the following A-eiits t: W. White, Chemist, Guildhall-square, Carmarthen; Mor- titner, do.; Mrs. Evans, near the Cross, do.; Morgan, Mei"- thyr Tydfil; Phillips, Cardiff; Williams, Brecon; ° Morgan, Abergavenny; Williams, Newport: Goulstone, Llandovery; tanor. ^eath, Monmouth Jones, Brecon; Phillips, Newport; «llliivns, Milford Harries and O. E. Davies, Haverfordwest; and by all Chemists and Medicine Vendors; or the Pro- prietors will send the Succedaneum free by post to any part of the Kingdom. LOSS OF TEETH. Messrs. HOWARD and THOMAS continue to supply the Loss of Teeth without springs or wires upon their new system Of SELF-ADHESION, which has procured them such um- versal approbation, and is recommended by numerous "hysicians and Surgeons as being the most ingenious system of supplying artificial teeth, hitherto invented. I hey adapt themselves over the most tender gums, or remaining stumps Without causing the least pain, rendering the operation of Extracting quite unnecessary. They are so nxoil as to fasten ?"y loose teeth where the gums have shrunk from the use of Calomel or other causes. They also beg to invite those not liking to undergo any painful operation, as practised by most ^embers of the profession, to inspect their painless yet ^fitietive system and in order that their improvements may -within "the reach of the most economical, they will con- tinue the same moderate charges. Messrs. HOWARD and THOMAS, Surgeon Den- lists, 64, Berners-street, Oxford-street, London. At home from ten till four. Those interested in the subject will find this statement of their superiority over all others, to be entirely and scru- pulously correct. Their new method of fixing Artificial Teeth has obtained e. approbation and recommendation of the following eminent Physicians and Suqeons :-Sir Jam. Clark, Bart, fhysieian toher Majesty; Dr. Locock, Physician Accoucheur to heT Majesty: Dr. Ferguson, Physician Accoucheur to her aJesty; Dr Bright, Physician Extraordinary to her Ma- IL ,.Itv ¡;;¡r B. C. Brodie. Bart., Serg. Surgeon to her Majesty, e late Sir A. Cooper, Bart. Serg. Surgeon to her Majesty; R. Pheate, Esq., Sergeant Surgeon to her Majesty. Dr. Merriman, I,h Y,Ician to her H. the Duchess of Kent; Sir C. M. Clark, yart., M.p.; Dr. Paris; Sir M. Tiertiey, Bart., M. D. Dr. !\mes Johnson; Dr. Chamber*; Dr. Conquest, and numerous other Members of the Medical Profession. ^ACTION. —Unprincipled individuals prepare the most DIrious compounds under the same names; they copy the ijjMs, bills, advertisements and testimonials uf tht; original Thomas's Succedaneum. It is therefore highly necessary to See that the words Howa.rd & Thomas are on the wrap- PC* of each article. ggf* All others are fraudulent Imitations. o THE SECRET INFIRMITIES OF YOUTH AND MATURITY. "WITH TWENTY-FIVE COLOURED ENGRAVINGS. Just Published, Sixteenth Thousand, in a sealed envelope, Price 2s. 6d., or post-paid, to any address for 3a. 6d. in P08tage Stamps, or Post- Office Order. ftELF-PRESERVATION a Medical Treatise on the Secret Infirmities and Disorders of Youth and Maturity. Illustrated with Twenty-five Coloured Plates, on the Anatomy, Physiology, and Diseases of the Urinary Clnd Reproductive Organs, explaining their various Structures, uses, and functions, and the injuries that are Produced in them, by solitary habits, and other excesses. With practical observations on the Treatment of Nervous debility, Local and Constitutional Weakness, Syphilis, Stricture, and other diseases of the Urethra. By SAIUEL LA'IIE RT, Consulting Surgeon, 9, Bedford- strect, Bedford-square, London, Matriculated Member of i e Uniycrsitv of Edinburgh, Honorary Member of the London Hospital Medical Society, Licentiate of Apothe- "azies, Hall, London, &c., &c. REVIEWS OF TIIE WORK. ?P author of this singular and talented work is a legally Q ified medica) man, who has endpntly had considerate Ox- Perieriee in the treatment of the varioui disorders, arising the follies and frailties of early indiscretion. The jr,'lgravings are an invaluable addition, by demonstrating the /^sequences of excesses, w hiph must act 'as a salutary warning «° youth and maturity, and by its perusa 1, many questions may 6 sa,hsfactonly replied to, that admit of no appeal, even to the ?oat confidential friend."—I nos TIES. I 'Ti; is decided) y the most scientific and yet most < "?CuigiMe work of the kind, we have ever yet perused and ?e engravings and explanations which accompany it, present jj^oral a. hli- instructive lesson, by detin?ating the evil !fects of ,N-0 fuf folly and excess. The subject is altogether tre,te in a very superior manner, AND THE AUTHOR BEING A ""OALLY QUALlFIIW IEDICAL UA, we recommend his work 0 Public notice with the utmost confidence."—RAILWAY BELL. Unquestionably this is a most extraordinary and skilful )trk, and ought to be ('xtenively circulated; for it is quite "'?ent that there are peculiar habits acquired at public nC ools and private seminaries, which are totally unknown !d concealed from the conductors of those establishments, rjd which cannot be too strongly reprobated and condemn- The engravings that accompany the work aro clear and Jrpbnatorv and being written by a duly qalitied medical petitioner, will doubtlessbe the means of saving many a £ °uth, as well as those of maturer age, from the various "vil consequences resulting from iii(ii!zeretio-iz;NIAONVT. d Published by the Author; and may be had at his resi- also from S. Gilbert, 52, Paternoster Row, and fannay and Co., 63, Oxford Street, London; Mr. hackdl, Bookseller, Guildhall Square, Carmarthen, S'jnnbrian Office, Swansea; Davey, 1, Broad St. Bristol; ijewton, 16, Church Street, Liverpool; and by all ooksellers. At Home for Consultation daily, from Nine till Two, 1'tnd from Five till Eight; and all letters immediately implied to, if containing the fee of JE1, for advice, &c.—9, "Bedford Street, Bedford Square, London. The work may be had in Carmarthen, of Mr. "hackell, Bookseller, Guildhall Square, price 2s. 6d or !nay be had post free, to any address, by enclosing 3s. 6d. 1,1 postage stamps to the author's residence. Messrs. R. and L. PERRY & Co. may be consulted .t 19, Berners-Street, Oxford-Street, London, daily, at 106, Duke-Street, Liverpool, every Thursday, Friday, and Saturday; & at 10, St. John-Street, Deans- ga,te, Manchester, on Mondays, Tuesdays, and AVed- iesdays. "THE SILENT FRIEND," :p ON HUMAN FRAILTY. rice 2s. 6d., and sent free to any part of the United Kingdom, in a Sealed Envelope, from either of the above Establishments on receipt of 3s. 6d. in Postage Stamps or Post Office Order. A MEDICAL Work on Physical Decay, Nervous "-A- Debility, Constitutional Weakness, excessive In- dulgence, &c. With Observations on Marriage, &c. With 10 fine Coloured Engravings on steel. ?y R. and L. PERRY and Co., Consulting Surgeons. ? Published by the Authors, and sold by Strange, 21, paternoster Row; Hannay & Co., 63, Oxford street: 'r",Irdon 146, Leadenhall-strcet, London; Newton, 16 ?d 19, Church-Street, Liverpool; llawle, Church-St., ijl*erpool; Ingham, Market-Street, Manchester; D. '?npbell, 136, ArgyIc-Street, Glasgow; R. Lindsay, "]Elnis Row, Edinburgh Powell, 10, Westmoreland, "?eet, Dublin; J. W. White, Guildhall-Square, Car- '?rthen, and by all Booksellers and Patent Medicine endors in Town and Country. OPINIONS OF THE PRESS. We regard the work before us, The SILENT FRIEND, as 11-ork embracing most clpar and practical views of a series Complaints hitherto little understood, and passed over by II. e majority of tlw Medical profession, for what reason we te at a loss to know. We must however confes that a Perusal of this work has left such a favourable impression on minds, that we not only recommend, but cordially wish i e!y one who is the victim of past folly, or suffering from discretion, to profit by the advice contained in its pages."— ge and Argus. 'The ut orsofTiiRSII.ENTFRIE%'Dseeymtob(tthorou,-hlv ,onversant with the treatment of a class of complaints which We fear, too prevalent in the present day. The per- ivenous style in which this book is written, and the va- elial le hints it conveys to those who are apprehensive of goring the marriage state, cannot fail to recommend it to Careful i)erusal.ERA. \t. 'This work should be read by all who value health and lsb to enjoy life, for the truisms therein contained, defy doubt."—"FAHMERS' JOULTNAL. j THE CORDIAL '? BALM OF SYRIACUM, b gentle stimulant and renovater in all cases of Y? ?bi);tv, whether Constitutional or acquired, nervous •h!u?tulity, irritation and consumption—by the use of il'ch the impaired System becomes gradually and ?ctu?IIy restored to pristine health and vigour. Sold b Ottles, price 11s. and 33s. The ?5 Cases may be ? as usual at their Establishment. THE CONCENTRATED DETERSIVE ESSENCE, anti-syphilitic remedy for Secondary Symptoms, th archin out and purifying the diseased humours of ce blood, removing all cutaneous eruptions, Scurvy, -onda, Pimples on the head, face, Ac. Price lis. 33g. per bottle. PERRY'S PURIFYING SPECIFIC PILLS, ? Price 2?. 9d., 4s. 6d. and 11s. per box, jj long been used with perfect success in all cases of ?Ounrrhn?a, Stricture, Inflammation, Irritation, &c. 1,heS° are free from mercury, eapaiva, and other de]? ??''i.nus dr"gs, and may be taken without interference ^n ? cWry instance. Sold by all medicine venders. s' Perry expect, when consulted by letter, the ti t,ilal of One Pound, to be addressed to the London ?t))"-shment, where all communications and orders are r? ?sted to be forwarded. ? A minute detail of the case is necessary. UsUaiSsrs- ?- and L. Perry & Co. may be consulted as usu:j'? ?' 19, Berners-strect, Oxford-Street, London, '?ilv ? at 106, Duke-Street, Liverpool, every Thurs- day p j ay ad Saturday, and at 10, St. John-Street, na?\p''?y, and Saturday, and at 10, St. John-Street, Alarichester, on Mondays, Tuesdays, and edllesd OY8, punctually, from 11 till 2, and ? till 8. ()I) 'S ""('aYs from 10 till 12. A l?"I't for Carmarthen, Mr. J. W. White, Chemist, all -Sa quare,ef whom may be had the Silent Friend.  FEMALE EDUCATION. CAMBRIAN SEMINARY, LANSDOWN HOUSE, TENBY. ESTABLISHED by a Lady and Gentleman of the first respectability and family connexions, more than twenty years residents of Tenby, for the instruction of their own and a limited number of the daughters of the aristocracy on the most approved principles of Home Education. The Establishment is governed by the regulations of the English and Parisian Seminaries now in greatest repute, and conducted by superintendents selected with much care from the professional talent of the metropolis, who (with their assistants) on a system suited to the present enlightened views of society, teach in their different departments English, French, Latin, Italian, German, Music, including Singing, Piano, Harp, and Guitar; Drawing, Painting, Dancing, Gymnastics, Embroidery, Plain and Fancy Needle Work, with every other requisite essential to a religious, elegant, useful, and highly finished education. Applications addressed to the superintendents of the establishment will immediately be replied to. SPECIAL NOTICE.—To SECURE THE ADVANTAGE OF THIS YEAR'S ENTRY, PROPOSALS MUST BE LODGED AT THE HEAD OFFICE, OR AT ANY OF THE SOCIETY'S AGENCIES, ON OR BEFORE 1st MARCH. MUTUAL ASSURANCE. SCOTTISH EQUITABLE LIFE ASSURANCE SOCIETY. INCORPORATED BY ROYAL CHARTER. EDINBURGH—26, ST. ANDREW SQUARE. LONDON—61, MOOItGATE-STREET. PRESIDENT. HIS GRACE THE DUKE OF BUCCLEUGH AND QUEENSBERRY. VICE-PRESIDENTS. THE RIGHT HON. LORD GRAY. THE RIGHT HON. LORD ABERCROMBY. The Assurances effected last year amounted to nearly THREE HUNDRED THOUSAND POUNDS. THE EXISTING ASSURANCES EXCEED TWO MILLIONS STERLING. THE ACCUMULATED FUND EXCEEDS THREE HUNDRED THOUSAND POUNDS. THE ANNUAL REVENUE EXCEEDS EIGHTY THOUSAND POUNDS. THE PROFITS ARE ALLOCATED AMONGST THE POLICY HOLDERS EVERY THREE YEARS. The next Allocation takes place at 1st March, 1847. The SCOTTISH EQUITABLE being a MUTUAL ASSURANCE SOCIETY, their Profits are not, as in Proprietary Companies, divided between the Partners of the Companies and the Assured. The WHOLE belong to the Policy Holders. These PROFITS or BONUSES may, in the Option of the Assured, be applied thus 1st, They may be ADDED TO THE SUM ASSURED payable at death or 2nd, They may be COMMUTED INTO A PRESENT PAYMENT to the Policy Holders or 3rd, They may be APPLIED IN REDUCTION OF THE FUTURE ANNUAL PREMIUMS. ADDITIONS TO POLICIES. At the Annual Meeting in May, 1844, LARGE BONUSES were made, besides reserving upwards of THIRTY THOUSAND POUNDS for future division. This reserved Fund is now increased to FIFTY THOUSAND POUNDS. EXAMPLE A Policy effected before 1st March, 1832 for E2000, is now increased to TWO THOUSAND STX HUNDRED AND FORTY FIVE POUNDS. If the person die after 1st March, 1846, his heirs will receive TWO THOUSAND SIX HUNDRED & NINETY- SIX POUNDS, being an addition of THIRTY-FIVE PER CEXT. on the sum assured. Other Policies in proportion. It is impossible for any Assurance Office to give greater advantages to Assurers than the Scottish Equitable affords. ROBERT CHRISTIE, Manager AGENT FOR PEMBROKE. JAMES R. BRYANT, Surgeon. MEDICAL REFEREE—Dr. J. W. PAYNTER. UNDER ROYAL PATRONAGE. I Perfect rt-eedo-ni from Cough in Ten Minutes after 'Use, and a Rapid CURE OF ASTHMA AND CONSUMPTION, AND ALL DISORDERS OF THE BREATH AND LUNGS, IS INSURED By Dr. LOCOCK'S Pulmonic Wafers. THE truly wonderful powers of this remedy have called forth Testimonials from all ranks of society, in all quarters of the world. The following have just been received More Cures in TREDEGAR. From Mr. J. P. NVilliai-iis, Chemist, Church-st., Tredegar. December 23rd, 1814. Gentlemen-A number of my friends have experienced great benefit through taking Locock s Wafers. Please to send me one dozen boxes by post, as some are waiting for them. I ° One friend, named Amy Calamore, subject to asthma, had a box last week, and has already received great benefit from them, although she did not take the whole, as she divided the box among some of her neighbours. Every one speaks highly of them, and they are taken by some of the first families in the town. Yours obediently, J. P. WILLIAMS. IMPORTANT TESTIMONIAL. From Mr. Owen Thomas, Wesleyan Minister, Holyhead. Oct. 9, 1845. "Dear Sir,-Dr. Locock's Wafers do a great deal of good to my voice. I got a bad cold from a damp bed thirty-five years ago, 'and my joice was very bad ever since being great pain to me when preaching and sing- ing—and I am very fond of singiiig. I used many different medicines, and some of tnrm do good for a lit- tle time but Dr. Locock's is the best of all-it clears my voice and stops the coughing instantly. I have ne- ver found anything yet to compare with them. I have been thirtv-three years a Wesleyan preacher, and all the Wesleyan Methodists in the principality know me, twenty years of which I have lived in Holy- head, and I am known personally to all the first men of that body, many of whom have admired the effects of the Wafers in clearing the voice, and stopping the cougli; they never got such a medicine before. "My wife, ever since Christinas, has been very well, after taking two boxes. I am a witness of their power to stop a frightful fit of coughing, in an instant. I, as a Wesleyan preacher, call upon all preachers and singers of every denomination, to take these Wafers for improving the voice, and curing Coughs. You may publish my testimonial for the excellent Wafers, if you wish. I am, yours truly, OWEN THOMAS." CURES OF CONSUMPTION. December 5th, 1845. Gentlemen,—Your Wafers I can speak of myself, with the greatest confidence, having recommended them in many cases of pulmonary consumption, and they have always afforded relief when everything else has failed, and the patients having been surfeited with medicine, I are delighted to meet with so efficient a remedy having such an agreeable taste, &c. Signed, J XO. MA wso, Surgeon. 13, Mosley-street, N ewcastle-on-Tyne. IMPORTANT TO ALL WHO SING. From S. PFARSALT,, Esq., of her Majesty's Concerts, and V icar choral of Lichfield Cathedral. Lichfield, July 10th, 1845. Gentlemen,—A lady of distinction having pointed out to me the qualities of Dr. Locock's Wafers, I was in- duced to make a trial of a box, and from this trial I am happy to give my testimonial in their favour—I find by allowin" g a fcw of the wafers (taken in the course of the day) to gradually dissolve in the mouth, my voice be- comes bright and clear, and the tone full and distinct. They are decidedly the most efficacious of any I have ever used. Signed, SAMUEL PEARSALL. The particulars of many hundred Cases may be had from every Agent throughout the Kingdom and on the Continent. DR. LOCOCK'S WAFERS give instant relief, and a rapid Cure of Asthmas, Consumptions, Coughs, Colds, and all Disorders of the Breath and Lungs. To SINGERS and PUBLIC SPEAKERS they are invaluable as in a few hours they remove all hoarseness, and increase the power and flexibility of the voice. They have a most pleasant taste. Price Is. 14d., 2s. 9d. and 11s. per box. Agent, Da Silva and Co., 1, Bride-lane, Fleet-street, London; J. W. White, Chemist, Carmarthen. CAUTION.—To protect the public from spurious imita- tions, Her Majesty's Honourable Commissioners have caused to be printed on the stamp outside each box the words DR LOCOCK'S WAFERS," in white letters on a red ground. If purchasers will attend to this Caution they will be sure to get the genuine article. 3" SOUTH WALES RAILWAY. NOTICE IS HEREBY GIVEN, that the NEXT HALF-YEARLY GENERAL MEETING of the Proprietors of this Company will be held, pursuant to the Act of Parliament, at the Paddington Station, Lon- don, on WEDNESDAY, the 25tli of FEBRUARY inst., at 12 for I o'clock precisely, for the Election of Four Directors and an Auditor, in the place of the same number, who will retire by rotation, and for other purposes of business. The chair will be taken at 1 o'clock precisely. CHARLES RUSSELL, Chairman. The Directors and Auditor retiring are re-eligible un- der the provisions of the Act. The transfer books will be closed on and after the 15th inst., and will not be re-opened until after the said Half- Yearly General Meeting on the 25th inst. By order, N. ARMSTRONG, Sec. South Wales Railway-office, 449, West Strand, London, February 4, 1846. SOUTH WALES RAILWAY, EXTENSION OF TIME FOR RECEIVING TENDERS FOR CONTRACTS FOR WORKS. NOTICE IS HEREBY GIVEN, that the Directors of the South Wales Railway Company will receive, on WEDNESDAY, the 11th of MARCH, 1846, at 12 o'clock, at their office. No. 449, West S rand, London, TENDERS for the EXECUTION of the three several CONTRACTS, extending from the river Lougher, through Swansea to Neath, being a distance of about 14 miles, and comprising tunnels and a large amount of earth work likewise of several contracts in the neighbourhood of Newport, com- prehending also a tunnel and other important works. Drawings and specification, may be seen at the respective offices of the resident Engineers at Swansea and at New- port, and printed forms of tender may be had at the same places, or at the Company's office in London, The Di- rectors will not consider themselves bound to accept the lowest or any tender. They request the parties to attend at the office of the Company in London at 2 o'clock on Wednesday, March 11, 1846. By order, N. ARMSTRONG, Sec. South Wales Railway-office, 449, West Strand, London. February 4, 1846. CAUTION.—All Persons advertising Succedaneum for Stopping decayed teeth, fraudulently attempt to imitate Mr. Clarke's original Succedaneum; and if any Succedaneum than Mr. Clarke's be purchased, it will be discovered useless. Mr. Clarke can say, without the slightest exaggeration, that he has sold 3,000 bottles of Succedaneum within 16 months; & 2,800 individuals have been able to use it successfully; and most of the other pur- chasers have been to Mr.Clarke, at his residence, 61, Lower Grosvenor-Street, London, to have their teeth stopped, without any further charge than the original cost of the Succedaneum, price os. Sold wholesale to all the che- mists in town and country; and none is genuine unless had through Messrs. Barclay and Sons, wholesale Medi- cine Warehouse, 95, Farringdon Street; Edwards and Son, 67, St. Paul's Church-yard; Hannay and Co., 63, Oxford Street; Colleck and Moseley, 139, Upper Thames Street, London and other respectable wholesale Medi- cine Warehouses or Mr. Clarke can send it by post to any part of the United Kingdom, on receiving a Post- office order. FOR STOPPING DECAYED TEETH, HOWEVER LARGE THE CAVITY. Patronised by Iler Majesty the Queen Dowager, Her Royal Highness the Duchess Gloucester, His Grace the Duke of Wellington, and the principal Nobility. Mr. CLARKE'S SUCCEDANEUM for Stopping Decayed Teeth is far superior to anything^everjiggj. before, as it is placed in the tooth without anypain, be- comes as hard as the enamel immediately after applica- tion, and remains firm in the tooth for life; not only rendering extraction unnecessary, but also making them again useful for mastication. All persons can use Mr. CLARKE'S Succedaneum themselves with ease, as full I directions are enclosed (price 5s.) and sold by all res- pectable medicine-vendors in town and country, and can be sent by post on receiving a Post-office order.—Pre- pared onlv by Mr. Clarke, Surgeon-de ti t, 61, -Grosvenor Street, Bond Street, (removed from 53, Harley-Street, Cavendish-Square.) LOSS OF TEETH. Mr. CLARKE still continues to supply the loss of teeth, from one to a complete set, upon his beautiful system of self-adhesion, which has procured ham such universal approbation in some thousands of iases; and recom- mended by Sir James Clark, bart., M.D., and Dr. Locock, Phvsicians to Her Majesty, and nurnarri ut, other mem- bers of the medical profession, as being the most in- genious system of supplying artificial teeth hitherto invented. They are so contrived, as to adapt themselves over the most tender gums or remaining stumps without causing the least pain, rendering the operation of ex- traction quite unnecessary and in order that his system may be within the reach of the most economical, he will continue the same moderate charges.—Mr. Clarke, Sur- geon-dentist, No. 61, Grosvenor-Street, Bond-Street, London.—At home from eleven till four. [BLAIR'S GOUT & RHEUMATIC PILLS. A seve)-e Case o A severe Case of Rheumatism, communicated by 11fr. Allen, Proprietor of the Nottingham Mercury." Mercury Office, Nottingham, March 17, 184-5. SIl,-I have the pleasure of forwarding you the par- ticulars of a case in which BLAIR'S GOUT and RHEUMATIC PILLS have proved eminently suc- cessful. A young woman, named Mary Wain, accompanied by her parents, who reside at Watnall, near this town, called upon 11-le' on Saturday last, being desirous of making her case known for the benefit of the public. It appears that Mary Wain had for some years past been a great sufferer from Rheumatism, but that in October last she was more than ordinarily afflicted, so much so that her father fetched her from her place of service, in order that she might have the attention of her mother at home at that time—to make use of the mother's description, she could not lift her hand to her mouth, or her foot the height of sixpence from the floor." Having heard of Blair's Pills, the father purchased a box at my shop about the second week in October the Pills took immediate effect, for I am assured by the parents and the girl herself, that on the following day she could not only lift her hand up to feed herself, but she could also move about on crutches. Since that time she has had five more boxes of the Pills, and, if I may judge from appearances, is as well as she ever was in her life, and has been so for some months past. I am, Sir, yours truly, To Mr. Prout, 229, Strand. RICHARD ALLEN. The never-failing effects of BLAIR'S GOUT and RHEUMATIC PILLS in curing every description of Gout and Rheumatism, have secured to then) a celebrity unequalled by any medicine of past or present times. They not only give relief in a few hours, but restore to perfect health in an inconceivably short space of time. They are equally speedy and certain in lumbago, sciatica, pains in the head or face, and indeed of every rheumatic or gouty affection; in fact, such has been the rapidity, i perfect ease, and complete safety of this medicine, that it has astonished all who have taken it, and there is scarcely a city, town, or village in the kingdom, but con- tains many grateful evidences of its benign influence. Sold by Thomas Prout, 229, Strand, London; price Is. Idi., and 2s. 9d. per box: and by his appointment by Mr. J. W. White, Chemist, Guildhall-Square, Carmar- then Mortimer, ditto Mrs. Evans, near the Cross do.; Morgan, Merthyr Tydfil: Phillips, Cardiff: Williams, Brecoii Morgan, Abergavenny; Williams, Newport; Goulstone, Llandovery; Fanor, Heath, Monmouth; Jones, Brecon; Phillips, Newport; Mathews, Aber- gavennv Williams, Milford: O. E. Davies, and Har- ries, Haverfordwest, J. S. Evans, Cardigan, and by the, venders of medicines generally throughout the kingdom. Ask for BLAIR'S GOUT AND RHEUMATIC PILLS and observe the name and address of Thomas Prout, 229, Strand, London," impressed upon the Government Stamp affixed to eaeh box of the Genuine Medicine. CARDIGANSHIRE TURNPIKE ROADS. STATEMENT OF THE RECEIPTS AND EXPENDITURE FOR THE YEAR 1845. ? RECEIPTS. ? ? REMARKS. £. 8. d. Z. So d. REMARJts. Fro!n Onicers of Trusts. 0 0 0 761 19 3 From Officers of Trusts 502 0 0 From Tolls-Upper I)istriet 225 2 0 Lower District 0. 1. 225 2 0 Fines 0 12 4 0 12 4 £ 1489 13 7 EXPENDITURE. BY COUNTY ROADS BOARD. I 0 0 153 0 1 To Public Works Loan Comnlissioners. 0 0 0 153 0 1 I ?"'  ?'    J   ? ..1 3 9 2 6 Salaries  139 2 6 New Toll Houses. 95 1 11 New Toll Boards, and removingandnxingdo.? 65 1 0 7 7 0 Printing and advertising.j"" 40 7 q LettingToIts. Letting Tolls ?g g 2 The local acts were re Debts of former Trusts 4 11 3 pealed on the 17th June, Miscellaneous 485 5 6 1815. BY DISTRICT ROADS BOARDS. UPPER DISTRICT. Labour. Tradesmen's Materials. Constant. Casual. Bills. Miscellaneous. £ s. d. £ s. d. £ s. d. £ s. d. E s. d. ;C s. d. Aberystwyth and A1b, erayron TR> oad J n 0 11 4 17 4 2 11 0 0 0 0 0 0 0 20 9 3 Machynlleth I? 12 10 II 4 12 0 4 13 S S 0 S S S S 26 17 8 Mact?nHeth. 0 0 0 »V 80 10 40 4 9 4 6 2 9 000 000 000 Meddya_Gerng °?3 ? 629 00 0 0 00 ?18130 DevilsBridge. ??' 4?34..0 13 0 000 000 9 13 5 Expended on the roads General Expenses .). 0 0 0 0 0 0 45 7 8 II 0 0 0 0 0 0 4.5 7 8 in July and August, and   not divided in the Ac- f43 12 0 18 2 0 59 7 5 0 0 0 0 0 0 121 1 5 counts. LOWER DISTRICT. Cardigan and Aberayron Road n 0 3 6 FI J 5 1I0 0 8 17 14 6 0 0 0 0 0 0 23 8 8 Kenarth. 0 „ JO 7 FL 0 0 0 0 0 0 23 9 9 Newcastle-Emlyn 0 u 6 3 0 0.. 2 18 8 21 2 0 0 0 0 0 0 0 24 3 8 Lampeter and Aberayron 0 0 0.. 2 2 8 19 0 4 0 0 0 0 0 0 21 3 0 Newcastle-Emlyn 1 3 0 4 8 0 10 4 6 0 0 0 0 0 0 15 15 6 General Expenses 0 ?" 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108 0 7 10807 JE212 3 17 0 0 88 8 4 0 0 0 0 0 0 E622 6 0 Balance in favor of the ———————— County Roads Fund. JE1489137 (Signed) H. D. HARNESS, CAPT. R. E. January 7th, 1846. GENERAL SUPERINTENDENT, TURNPIKE ROADS IN SOUTH WALES. CARDIGANSHIRE TURNPIKE ROADS. ESTIMATE OF THE RECEIPTS AND EXPENDITURE FOR THE YEAR 1846. RECEIPTS. Balance .in the hands of the Treasurer  9  Deduct Bills and paylists noTt rdeealisvuerreer dI111111111 1111111111IV. 11111111 6631 9 9 3 33 True balance. 622 6 0 Probable receipts from Tolls in the Upper District. 1500 0 0 OJ In the Lower District. ïOO 0 0 2200 0 0 From County Treasurer:—Composition for Bridges. 0 o 0 County Roads Rate. "?" ?; '?"?;J?;?.JJ. JJ;J;;JJ?J?.J;J;?J  2822 6 0 EXPENDITURE. BY COUNTY ROADS BOARD. To Public Works Loan Commissioners. 618170 Salaries 240 0 0 RentofTollHouses. .?.?. 8 o 16 q 0 Rent of Toll Houses Expense of paying labourers 6 0 0 Premiums to constant labourers. 6 0 0 Stationery, printing, and advertising ?Q o o New Toll House for the West Gate at Aberayron 20 0 q New Toll'House for the West Gate at Aberayron ? Contingencies 100 0 0 444 16 0 BY DISTRICT ROADS BOABDS. UPPER DISTRICT: Labour. Repairs of Materials. Constant. Casual. Toll houses. Miscellaneous. £ s. d. JE.s. d. JE.?. ?. ?. 8. d. ??.? f.??? Aberystwyth and Aberayron RT>oad I J mo 0 0 52 0 0 15 0 0 2 10 0 0 10 0 170 0 0 Aberyst?-yth?dAberayronRT, oad. ? inn 60 0 0 15 0 0 4 10 0 3 10 0 203 0 0 Machynlleth 120 0 0 60 0 0 15 0 0 4 10 0 3 100 203 0 0 1Peiidryn 14 0 0 18 0 0 3 0 0 0 0 0 0 00 35 0 0 Steddva-Gerig 1'500 0 78 0 0 15 0 0 6 0 0 6 00 2,5,50 o Devil's Bridge 85 0 o 52 0 0 20 0 0 2 0 0 10 00 169 0 0 Lighting Gates 0 0 0 0 0 0 0 0 0 0 0 0 14 00 14 0 0 Contingencies and general expenses .» 0 0 0 •0 00.. 0 0 0 0 0 0 50 00 50 00 E469 0 0 260 0 0 68 0 0 15 0 0 84 0 0 896 0 0 LOWER DISTRICT. C,vdigf»dAbe„yronB»d. N J « « 0 0 g » » ,7 J » •; • • { J li ciiartli 50 o 0 26 0 0 15 0 0  o oo 10100 Neweast???11-?il)-n 40 0 o 26 0 0 1() 0 0 2 0   00  S Lan.pett, and Aberayron ? 0 S ? S 0 S X j » 3 0 0 J g » ? J 1m 62 0 00 1, tn 1 peter atid A.borayron • 0 i 0 0 0 162 0 0 XTOstlc-tn.ljTi H0 0 I 0 0 0 0.. 0 0 0 0 0 0 18 0 0 18 0 0 L ightin,Gates 0 0 o o o o 0 0 0 0 0 018 00 8 0 0 ?S?ud-general-e??????0 0 0 ? ?00 •• •• 50 0 0  713 0 0 ?300 0 0 208 0 0 100 0 0 37 0 0 68 0 0 ?3 0 Probable balce at the end of 1846. £ 2822 6 0 Charges upon the County, executed by South Wales Commissioners, or Secretary of State, and AlInuities payable. D te Amount of Charges. Annuity. Termination of Annuity, 1(JIC I' £ 5828 14 7 £ 306 0 2 26th March, 1875. 1 0 ? 29th Sen 1845. •• 4634 0 3 243 5 8 30th Sept. 1875. Probable amount of t?e payment that will be due in Sept. 1846, on account of the charge to be made in Marc? 69 I1 2 E618 17 0 (Signed) H. D. HARNESS, CAPT. R. E. January 7th, 1846. GENERAL SUPERINTENDENT, TURNPIKE ROADS IN SOCTll WALES. rp THE "BLACK STAR" LINE OF PACKET SHIPS. ISMGS LIVERPOOL TO NEW YORK. Captains. Tons Beg. Tons Bur. Sea T. F.Freeman. 807 1400 Liberty .P. P. Norton 692 1300 Cornelia F. M. French. 1040 1750 Ohio .H.Lyon 768 137.5 Tarolinta J.G.Smith 604 •• 1100 Samuel Hicks ..T. G. Bunker 850 1500 Shenandoah .J. West 804 .1400 Empire J. G. Russell 1190 1900 Pa)?tltea W. B. Lane i23.. 1;2.) Indiana James D. Bennett.. 710 1300 Huguenot S. Goodhue 934 1600 C'«?i«f/tr(newship) W. Edwards. 950 1660 THEY arc all first-class New York ships, built of the JL choicest and best materials, and well-known as remarkably fast sailers. Their commanders arc men of long experience and nautical judgement, and well acquainted with the trade. The cabins are fitted up handsomely and commodiously for cabin passengers, who are found with everything ex- cept liquors and wines, at a rate of passage not exceed- ing sixteen guineas. The second cabins and steerages are lofty and airy, and in every way adapted to promote the comfort and health of passengers, at a cheap rate, finding their own provisions, except bread stuffs. The appointed days of sailing will be strictly ad- hered to. Apply to C. GRIMSHAW & Co., 10, Goree Piazzas. Liverpool, 1845. Emigrants will have every information given them, on application by letter. Sums of money revived in Liverpool, either by post or otherwise, will be paid in New York on demand, or remitted to any part of America, free of any charge. AGENTS IX AMERICA, SAMUEL THOMPSON & NEPHEW, 273, Pearl-street, New York. STEAM COMMUNICATION BETWEEN" Liverpool and Bristol, calling at Swansea and Milford, During the Month of FEBRUARY, 1846. <*S THE NEW AXD POWERFUL < 1 IROX STEAM SHIP, TROUBADOUR, JAMES BECKETT, Commander IS intended to Sail from Trafalgar Dock, Liverpool, with Goods and Passengers, for BRISTOL and SWANSEA, CALLIXO AT MILFORD. Tuesday, Feb. 10 9 10rn ] Saturday, Feb. 28 11 morn Friday. O. 4 after. I Sat;irdav,Fel,.28 11 morn From BRISTOL CALLING AT SWANSEA, & IMILFORD Wednes., Feb. 4 11 morn Tuesday, Fob. 24 5 morn Saturday, 14. 7 morn FROM SWANSEA. Thursday, F,h. 9 morn I Wednes., Feb. 25 5 morn Monday — 16. 6 mor FAKES:—To Liverpool, Cabin, El Steward's Fee, 2s. 6d.; Deck, 7s. 6d. Goods intended for the above Steamer, from Liverpool, must be at the Trafalgar Dock two hours before the ad- vertised hours of sailing. Goods forwarded free of Commission. All Freights paid on delivery of the Goods, and land- ing and warehousing at the expense and risk of the Consignee. (ggf Goods carefully forwarcleded to Neath, Aberavon, Llandilo, Llangadock, Llandovery, Llanwrtyd, and Llan- gammarch Wells, &c. &c., by PltlCE's VAN, which leaves Swansea for those places every Wednesday morn- ing at ten o'clock. BRISTOL GENERAL STEAM NAVIGATION COMPANY O?ce I, Q??y, ?r??oJ. THE following STEAM VESSELS are intended to JL Sail from CUMBERLAND B.VSIN, BRISTOL, and as under mentioned, with or without Pilots, and with liber- ty to tow Vessels, during the Month of FEBRUARY, 1846. FOR CARMARTHEN, CALLING AT TENBY, PHCENIX. Friday, Feb. 6. 2 after. Friday, Feb. 20 11,morn Friday, — 13. 7 morn Friday, 27 7 morn FROM CARMARTHEN, CALLING AT TENBY, PIKENIX. Tuesday, Feb. 3. 9,morii I Tuesday, Feb. IT. 7morn Tuesday, 10. 4 after. | Tuesday, 24. 3 after. FOR DUBLIN. VICTORY, Fridays. Friday, Feb, 6 2 after. I Frday, Feb. 20 lUmorn Fnùay, 13. 7 inuril IFri(lav, Feb. 20 I7ll'morn Fri,li,  27 ?llorft Returns Tuesdays. FOR CORK. ROSE, Tuesdays.—SABRINA, Fridays. Tuesday, Feb. 3 lOjmorn Tuesday, Feb. 17. 9 morn Friday, — 6. 2 after. Friday, 20.11\morn Tuesday, — 10. 5 after. Tuesday, — 24. 4 after. Friday, — 13. 7 morn Friday, — 27 7 morn Return Tuesdays and Fridays. FOR W ATERFORD.. NORA CREINA, Tuesdays.—OSPREY, Fridays. Tuesday, Feb. 3.lOjmorn Tuc?,da?-, Fell. 8i;morii Friday, 6. 2 after Friday, —20.11'mo? Te3da, 10 6 morn Tuesday, — 24 4 after. Friday, 13 7 m.orr. ti I T ue?dzty, 2 4 4' after. Friday, 13. 7 morn Friday, 27. 7 morn Iteturn I uesdays and Fridays. FOR TENBY. STAR, Tuesdays—PHCENIX, Fridavs. Tuesday, Feb. 3 10,morn i Tuesday, Feb. i7.8?morn Friday, 6 2 after. Friday, — 20 ll^morn Tuesday, .-10 6 morn I Tuesday, — 24 5 mum Kridm i3.W7 morn Friday, 27. 7 morn Fnda?, FIWM TENBY. PHCENIX, Tuesdays.—STAR, Saturdays. Tuesday, Feb. 3.12,}aiter. Tuesday, Feb. 17.tO?morn aIUrdåy, 7 ^morn I Saturday, :H. I morn 'lue?day 7 E'tter Tuesday, —24.Batter. Saturùay, — 14. 8 morn Tuesda.N, 24 6 after. SaturdaMy, ILFORD, PATER & HAVERFORDWEST FOR MILFOIW, P AIEl{, &- HA VERFOIWWEST CALLING AT TENBY. STAR. Tuesday, Feb. 3 ol,morii 'I'uesda- Feb. I Ttiesda 10. 0 mom Tuesday, — 24 o mom Tuesday, HAVERFORDWEST, CALLING AT PATER, FROM MILFORD & TENBY STAR. Friday, Feb. 6. 1 after. Friday, Feb. 20.11 morn fnùa,y, 13. ,morn Friday, :n. 7 morn FROM MILFORD. STAR. Friday, Feb. 6 9'after k'rida3-, Feb. 20. 7 after. Friday, Feb. 14. 2 inoi-ii I Saturday, 28. 2 morn Saturday, FOR SWANSEA. COUNTY-Tuesdays & Fridays. BERESFORD—Thursdays & Saturdays. Tuesday, Feb. 3.11 morn I Tuesday, Feb. 17 9Jmorn Thursday, I morn Thursday, 19.lUmuTl\ Friday, 6. 2 morn Friday, — 20 ll^morn Saturday, 7 4 morn j Saturday, — 21 12 noun. Tuesday, 10. (; murll Tuesday, — 24 5 morn Thursday, 12 7 morn l Thursda" y. 26. 6morn Friday, 13. muni Friday, 27. 7morn Saturday 14. 8 morn Saturday, :.18. 8 morn FROM SWANSEA. BERESFORD—Tuesdays & Fridays. CO UTY -Thursd,ns & Saturdays. Tuesday, Feb. 3.11 morn i Tuesday, Feb. 1 10'morn Thursday — 5. i?morn J Thursday, —H).ll.?mom Friday, 6. 2,morn Friday, 20 ll^morn Saturday, — 7. 4 mum aturda)', 21. 2 morn :j:l\csda:, 1. I morn I i'uesday, — 24 (j morn Thursd?; 12 7.'Jmorn Thursday, — 7 morn Friday, IJ. 8 morn llridan?, 8 inorn Saturday, — 14. 8 mom Saturday, — 28. 8 morn FROM BRISTOL. LADY CHARLOTTE—Mondays, Wednesdays, and Fridays. PRINCE OF WALES—Tuesdays, Thursdays and Saturdays. Jonday, Feb. 2 n'¡morn I Monday, Feb. 16. 8 moru Tuesday, 3 lOjmorn Tuesday, 17. 9 morn Wednesday,— 4 11 morn Wednes., — 18 9 morn Thursday, 5.lifter. Thursday, —19.)0morn Friday — 6. 1!,after. Friday, — 20 11 morn Saturday, — 7. I., fafter. '21 12,1,-fter. Monday — 9 5 morn Monday, — 23 *7 mora Tuesday, — 10 SJmorn T?lesdai — 24 *7^morn Wednesday,— 11. 5,1,morn 'v?n4 c(d' n ee; r"?',ay, 2 morn Thursday, -12. 6morn Thursday, — 26 6 morn Fridav —13. 6 Unorn ?'ri(la — 27 T>morn S.turd.y. "-FitiTc/ilDirf: "••••Ilmorn PRINCE OF WALES—Mondays, Wednesdays, and Fridays. LADY CHARLOTTE—Tuesday:, Thursdays, and Saturdays. Monday, Feb. 2. 8 morn lon<*a.v- Feb. 16. 6'jmorn Tuesday, — 3.S?morn £ Tuesday, 17 7 mo_ ?Msday,- 4. 9 morn ?dnesday,- 18 8 morn Thurs,la.?-, 5.1?after. Thursday, — 19. 8 morn prid?y 6. 12 noon. tnday, 20.9 morn Saturday, 7. laner I Satu 21 11 (,ri Monday, 9 3 aftor. Monday, — 2.S. 1.) after. 24 3 al'ter. Wednesday,— J 1 5 mom I V\ednesday,— 2.) SJatter Thursda* y, 12. 5 morn Thursday, 26. morn 1 2 'iday, —2 7  m.irn Friday, — 13. 5morn Friday, 2i.J morn Satui-da),, morr, Saturday, 28. "morn Those marked ^Oiin l&ssage. The whole of the above Vessels are iitted up for the conveyance of passengers and goods. I cmale Stewards on Board.—Carriages and Horses shipped with care. Horses and Carriages to be shipped two hours before sailing. Particulars may be obtained by applying at the Bristol Steam Navigation Company's Office, Quay, Bristol; where all Goods, Packages, Parcels, &c., should be addressed for Swansea, to \V. Terrell & Sons, :"3, Back; and G. C. Glasson, 12, QUit)" streetfor Cardiff, to 1.II. Johnson, Clare street Hall, Marsh street:—and for Newport, to J. Jones, ltownham Wharf, Hotwells. AGENTS.—Mr. R. STACEY, Carmarthen Mr. George Hughes, Tenby; Mr. John Rees, Haverfordwest, Mr. Palmer, Milford Mr. Bowen, Pater Mr. John N. Smart, and Mr. E. T. Turner, Swansea; Mr. Pridham, Bideford Mr. Martin, Ilfracombe and Mr. J. Clarke, Lynton. "NOTICE. The Proprietors of the above Steam Packets will not be accountable for any Cabin Passenger's Luggage, (if lost or damaged) above the value of £ 5: nor for any Passen- ger's Luggage (iflost or damaged} above the value of2Ms. un- less in each ease entered as such, and freight in proportion paid for at the time of delivery; norwillthey be answerable for any other parcel above the value of 10s. (iflost or damaged} unless entered as such, and freight III propvrtion paill lor the same at the time ofdetiveri. Not accountable for any Goods without Shipping Notef. All letters seeking information to be post paid. Bristol, February, 1846. ROWLAND'S KALYDOR AN EASTERN BOTANICAL DISCOVERY OF SURPRISING LFPICACY FOlt RENDERING THE SKIN SOFT, CLEAR, AND FAIR, And for bestowing a healthy roseate lll/u on tha COMPLEXION. AS a CREATOR and CONSERVATOR of a transpa- rently fair skin, ROWLAND'S KALYDOU may be said to exert an almost maeical power. BALMY, ODORIFEROUS, CREAMY, and free from all mineral admixture, it is distinguished for its ex- tremely bland, purifying, and soothing effect upon the skin while by its action on the pores and minute secretery vessels, it expels all impurities from the surface, allays every tendency to inflammation, and thus etfectuailv dissipates all REDNESS, TAN. PDI- PLES, SPOTS, FRECKLES, DISCOLORATION*, and other unsightly Cutaneous Visitations. The radiant bloom ititiiparts t,) the CHEEK: the softness and delicacy which it induces on the HANDS, ARMS, and NECK; its capability of soothing irritation, re- moving Cutaneous Defects, and all unsightly appear- ances, render it indispensable to every Toilet. The constant and persevering use of this invaluable medicament preserves and in/igorates those important functions of the Skin on which depend its purity and softness—the Neck, Hands and Arms assuming and retaining the radiant whiteness so much admired, and affording so unequivocal a mark of attention to the niceties of the Toilet and the graces of Personal Attraction. To GENTLEMEN, who suffer from tenderness and irritation of the face after Shaving, ROWLAND'S KALTDOR will have an unrivalled effect in alleviating and allaying irritation and smarting pain, and render- ing the skin soft and smooth. It is invaluable as a rf-novating and refreshing Wash during the heat and dust of Summer, or Frost and Bleali Winds of Winter; and, in case of Sun-burn, Stings of Insects, Chilblains, Chapped-Skin, or Inci- dental Inflammation, its virtues have long and extensively been acknowledged. Its purifying and refreshing properties have obtained its exclusive selection by the Court, and the Itoyal Family (f Great Britain, and those of the Continent of Euro7 e, together with the 11 elite" of the Aristocracy and Iiau'e Volee;" from the sultry climes of India, and the Drawing-rooms of Calcutta and Madras, to the frozen realms of the Czar and the SALONS of St. Petersburg and Moscow. This exotic preparation is perfectly innoxious, acting in all cases by promoting a healthy tone of the minute vessels, and is tite most elegant as irell as effective Toilet appendage hitherto submitted to universal patronage. THE NURSERY.-One of the most important uses of this invaluable Preparation is its peculiar adapta- tion for the use of Children and the purposes of the Nursery. As a wash for Infants it cannot be too strongly recommended cooling, healing, and innox- ious, it may be used by the most delicate lady or child with assurance of the most perfect safety and effect: it preserves and beautifies the young and tender skin, and ensures it from derangement by external causes. LADIES who, while nursing, suffer pain from sore or inflamed nipples, will find an unfailing relief in the KALYDOR; and from its peculiar power to allay irritation and cool the mouth, it renders pleasing and painless that most delightful task imposed by ma- ternal duty. CAUTION.—Its high and universal reputation causes UNPRINCIPLED SHOP-KEEPERS to offer spurious Compounds for sale underthethe title of KALYDOR," composed of mineral astringents utterly ruinous to the Complexion, and by their repellent action endangering health. It is therefore imperative on purchasers to see that the words ROWLAND'S KALYDOR" are on the Envelope (an Engraving of exquisite beauty from a steel plate by Messrs. PERKINS, BACON AND CO. To protect the Public from Fraud, The Iloll. Cum- missioners of Stamps have directed the Proprietors' Name and address thus—A. ROWLAND AND SUN, 20, Hatton Garden to be engraved on the Government Stamp which is affixed on each bottle. Price 4s. ûd. and 8s. 6d. per Bottle. Sold by the Proprietors, and by Chemists and Perfumers. All other KALYDORS" are FRAUDULENT IMITATIONS. ALL MAY BE CURED BY HOLL^VA\^S OINTMENT. FIFTY ULCERS CURED IX SIX WEEKS. Exti-act of a Letter from John Martin, Esq., Chronicle" Office, Tobago, IVest Indies February 4th, 1845. To PROFESSOR HOLLOWAY. Sir,—I beg to inform you that the inhabitants of this Island, especially those who cannot afford to employ medical gentlemen, are very anxious of having your astonishing Medicines within their reach, from the im- mense benefits some of them have derived from their use, as they have been found here, in several cases, to cure Sores and Ulcers of the most malignant and des- perate kind. One gentleman in this Island, who had, I believe, about fifty running ulcers about his legs, arms, and body, who had tried all other Medicines before the arrival of yours, but all of which did him no good; but yours cured him in about six weeks, and he is now, by their means alone, quite restored to health and vigour. (Signed) JOHN MARTIN. PILES, FISTULAS, AND BEARINGS-DOWN. A remarkable Cure by these Pills and Ointment.—A half-pay lieutenant, lately residing at St. Heliers, Jersey, whose name by request is omitted, had for three years suffered from piles and fistula, besides a general bearing down, of the most distressing nature. He had twice undergone an operation, but to no purpose, and at last gave himself up to despair. Yet, notwithstanding this complication of complaints, together with a debilitated constitution, he was completely cured of all his infir- mities and restored to the full enjoyment of health by these justly renowned medicines, when every other means had failed. Extraordinary Cure in the West Indies, of Leprosy and other direful skin diseases. June 3rd, 1844. Mr. Lewis Reedon, of Georgetown, Demerara, written under the above date-that Holloway's Pills and Oint- ment have cured bad legs that no doctor could manage- ulcers and sores that were of the most drcadfal descrip- tion as likewise leprosy, blotches, scales and other skin diseases of the most frightful nature, and that the- cures effected there by these wonderful medicines are so nume- rous and extraordinary as to astonish the whole population. Canccrcd Breast.— A Wonderful Circumstance. Copy of a Letter from Richard Bull, Bootmaker, Tatton, near Southampton. February 9th, 1845. To PROFESSOR HOLLOWAY. "STR,-The Lord has permitted to be wrought a wonderful cure of Cancers or Abscesses, of twelve years' standing, in my wife's breast. In the latter part of the time, eleven wounds were open at once. The Faculty declared the case as past cure, several pieces of bone had come away, and I expected that my poor wife would soon have been taken from me. It was then that a friend recommended the use of your Pills and Ointment, which to our utter astonishment, in the space of about three months, healed up the breast as soundly as ever it was in her life. 11 1 shall ever remain Your most grateful and obedient servant, (Signed) "RICHARD BULL." Wheezing on the Chest and Shortness of Breath. Copy of a Letter from Mr. Jeremiah Casey, So. 1, Compton-place, Compton-street, Brunsicick-squarc, London, April 25th, 1845. To PROFESSOR HOLLOWAY. SIR,-I beg to inform you that I believe I had been for more than three years, one of the greatest sufferersin the world with Chronic Asthma. For weeks together my breath was frequently so short that I was afraid every moment of being chokcd with phlegm. I never went into abed; very often, indeed, I have been obliged to pass the night without being able to recline sufficiently to lay my head on a table, lest I should be suffocated. No one thought I should live over the winter, nor did I expect it myself; but I am happy to say that I am now able to work from morning to night, and that I sleep as well as, ever I did in my life and this miracle (I may say) was effected by rubbing your invaluable Ointment twice a day into my chest, and taking ten of your Pills at bed-time, and ten again in the morning, for about three months. (Signed) 0 JEREMIAH CASEY. In all Diseases of the Skin, Bad Legs, Old Wounds and Ulcers, Bad Breasts, Sore Nipples, Stoney and Ulcerated Cancers, Tumours, Swellings, Gout, Rheu- matism, and Lumbago, likewise in cases of Piles Holloway's Pills, in all the above cases, ought to be used with the Ointment; as by this means cures will be effected with a much greater certainty, and in half the time that it would require by using the Ointment alone, The Ointment is proved to be a certain remedy for the bite of Moscliettoes, Sand-flies, Chiego-foot, Yaws, and Coco-bav and all skin Diseases, common to the East and West Indies, and other tropical climes. Burns, Scalds, Chilblains, Chapped Hands and Lips, also Bunions and Soft Corns, will be immediately cured by the use of the Ointment. Sold by the Proprietor, 214, Strand, (near Temple Bar,) London, and by ad respectable T. endors of Patent Medi- cines throughout the Civilized World, in Pots and Boxes, at Is. lid., 2s. 9d., 4s. 6d., 11s., 22s., and 33s. each. There is a very considerable saving in taking the larger sizes.